產(chǎn)品描述

塔望科技研發(fā)的全身體積描記系統(tǒng)（whole-body plethysmograph，WBP）可對清醒自由活動動物呼吸參數(shù)進(jìn)行測量，如呼吸頻率，潮氣量，氣道高反應(yīng)性測試（Airway hyperresponsiveness，AHR）等。測試過程中，動物可以處于清醒自由狀態(tài)，避免了創(chuàng)傷性氣管切開及麻醉的影響，使實(shí)驗(yàn)過程更加簡便，用于呼吸系統(tǒng)模型動物對藥物等反應(yīng)性研究，呼吸性藥物的藥理和毒理學(xué)研究，特別適合于大批量動物快速初篩試驗(yàn)，適合長期跟蹤研究和重復(fù)性篩查。

產(chǎn)品特點(diǎn)

· 不需要做手術(shù)，操作簡單

· 可多通道同時(shí)監(jiān)測

· 可在動物在自然狀態(tài)下呼吸的研究以及長期跟蹤實(shí)驗(yàn)，適合進(jìn)行藥物初篩

· 具有藥物氣溶膠霧化模塊· 具有自動標(biāo)定功能

· 具有飲水口和食物口，可進(jìn)行長期連續(xù)監(jiān)測

· 可選配測量心電、血壓、體溫、心率等指標(biāo)，可與植入式遙測設(shè)備聯(lián)合使用

· 具有分析軟件，數(shù)據(jù)可保存至excel或txt格式

可選配的功能模塊：

· 同步視頻監(jiān)測：同步的視頻錄像文件

· 咳嗽檢測：通過軟件自動監(jiān)測咳嗽事件

· 其它生理指標(biāo)測量：可在麻醉或清醒狀態(tài)下測量心電、血壓、體溫、心率等指標(biāo)，可與植入式遙測設(shè)備聯(lián)合使用

檢測參數(shù)

Ti：吸氣時(shí)間（s）

Te：呼氣時(shí)間（s）

PIF：最大吸氣流速（ml/s）

PEF：最大呼氣流速（ml/s）

Volbal：吸氣時(shí)間/呼氣時(shí)間

F：呼吸頻率（次/min）

Vt：潮氣量（ml）

Mv：分鐘通氣量（ml）

AV：累積體積（ml）

EF50：呼出50%氣量時(shí)對應(yīng)的呼氣流速（ml/s）

EIP：吸氣末暫停時(shí)間

EEP：呼氣末暫停時(shí)間

TR：松弛時(shí)間

PenH：增強(qiáng)呼氣間歇（enhanced pause）

Rpef：相對時(shí)間

適用領(lǐng)域

· 各種呼吸疾病研究，如：哮喘、肺纖維化、肺損傷、ARDS、肺癌等

· 安全藥理：藥物對呼吸系統(tǒng)的影響

· 睡眠呼吸：監(jiān)測動物低通氣、阻塞性呼吸暫停等

· 環(huán)境毒理：環(huán)境污染物對動物呼吸的影響

· 吸入式毒理：染毒物質(zhì)對呼吸系統(tǒng)的毒性影響

· 高原醫(yī)學(xué)：高原環(huán)境對呼吸系統(tǒng)的影響

· 其它需要對呼吸參數(shù)評價(jià)的場合

相關(guān)文獻(xiàn)

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